Description

3-Ethoxy-4-Fluoro-5-(Trifluoromethyl)Phenylboronic Acid is a high-purity, multi-functionalized boronic acid derivative essential for modern synthetic chemistry. Its value lies in its role as a key building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. This advanced intermediate is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block in Suzuki-Miyaura cross-coupling reactions for synthesizing complex drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the trifluoromethyl and fluoro substituents for enhanced biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for creating novel organic electronic materials, such as those used in OLEDs and semiconductors, where the specific substitution pattern influences electronic properties.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.

Basic Information

Product Name	3-Ethoxy-4-Fluoro-5-(Trifluoromethyl)Phenylboronic Acid
CAS No.	2096341-62-5
Molecular Formula	C9H9BF4O3
Molecular Weight	251.98 g/mol
Synonyms	[3-Ethoxy-4-fluoro-5-(trifluoromethyl)phenyl]boronic acid; 3-Ethoxy-4-fluoro-5-(trifluoromethyl)benzeneboronic acid; (3-Ethoxy-4-fluoro-5-(trifluoromethyl)phenyl)boronic acid; Boronic acid, B-[3-ethoxy-4-fluoro-5-(trifluoromethyl)phenyl]-; 2096341-62-5; 3-Ethoxy-4-fluoro-5-trifluoromethylphenylboronic acid
EINECS	Contact for details

Quality Control

Our 3-Ethoxy-4-Fluoro-5-(Trifluoromethyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.