Description

3-(1-Cyanocyclopropyl)-2-Fluorophenylboronic Acid is a specialized boronic acid derivative featuring a unique cyanocyclopropyl substituent. This compound is a high-value pharmaceutical intermediate and Suzuki-Miyaura cross-coupling reagent critical for constructing complex fluorinated biaryl structures. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in oncology and CNS therapeutic areas.
• Suzuki-Miyaura Cross-Coupling: Essential reagent for forming carbon-carbon bonds between aryl halides and this boronic acid, enabling the creation of complex, functionalized biaryl scaffolds.
• Agrochemical Research: Used in the development of new pesticides and herbicides where the fluorinated phenyl moiety can enhance biological activity and stability.
• Material Science: Potential monomer or precursor for advanced organic electronic materials and liquid crystals.
• Chemical Biology: Useful as a probe or linker in bioconjugation chemistry due to the reactivity of the boronic acid and nitrile groups.

Basic Information

Product Name	3-(1-Cyanocyclopropyl)-2-Fluorophenylboronic Acid
CAS No.	2096341-54-5
Molecular Formula	C10H9BFNO2
Molecular Weight	205.00 g/mol
Synonyms	[3-(1-Cyano-1-cyclopropyl)-2-fluorophenyl]boronic acid; 2-Fluoro-3-(1-cyanocyclopropyl)benzeneboronic acid; 3-(1-Cyanocycloprpyl)-2-fluorobenzeneboronic acid; B-[3-(1-Cyanocyclopropyl)-2-fluorophenyl]boronic acid; 2096341-54-5; Boronic acid, B-[3-(1-cyano-1-cyclopropyl)-2-fluorophenyl]-; 3-(Cyanocyclopropyl)-2-fluorophenylboronic acid
EINECS	Contact for details

Quality Control

Our 3-(1-Cyanocyclopropyl)-2-Fluorophenylboronic Acid is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.