Description

2,4-Difluoro-3-(2-Methoxyethoxy)-5-Methylphenylboronic Acid is a high-value, multi-functional boronic acid derivative essential for modern synthetic chemistry. Its primary value lies in its role as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is critically needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that benefit from its unique fluorinated aromatic structure.
• Material Science Research: Serves as a monomer or precursor for creating novel organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Ligand and Catalyst Development: Employed in the synthesis of sophisticated ligands for transition metal catalysis and organocatalysis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and sensors for biological target identification and validation.
• Custom Synthesis and Contract Manufacturing: A vital reagent for custom synthesis houses and CROs/CMOs serving the global life sciences market.

Basic Information

Item	Details
Product Name	2,4-Difluoro-3-(2-Methoxyethoxy)-5-Methylphenylboronic Acid
CAS No.	2096341-45-4
Molecular Formula	C₁₀H₁₃BF₂O₄
Molecular Weight	258.02 g/mol
Synonyms	2,4-Difluoro-3-(2-methoxyethoxy)-5-methylbenzeneboronic acid; [3-(2-Methoxyethoxy)-2,4-difluoro-5-methylphenyl]boronic acid; 5-Methyl-2,4-difluoro-3-(2-methoxyethoxy)phenylboronic acid; Boronic acid, B-[3-(2-methoxyethoxy)-2,4-difluoro-5-methylphenyl]-; 2096341-45-4; Difluoromethoxyethoxymethylphenylboronic acid
EINECS	Contact for details

Quality Control

Every batch of 2,4-Difluoro-3-(2-Methoxyethoxy)-5-Methylphenylboronic Acid is manufactured under strict quality management systems. We employ advanced analytical techniques including NMR (¹H, ¹³C, ¹⁹F, ¹¹B), HPLC, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent moisture absorption and degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.