Description

4-Fluoro-2-(Morpholinomethyl)Phenylboronic Acid Pinacol Ester Hydrochloride is a high-value, advanced pharmaceutical intermediate and building block for organic synthesis. This compound matters for its crucial role in facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl structures. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the discovery and production of novel active compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing complex fluorinated biaryl motifs.
• Suzuki-Miyaura Cross-Coupling: Serves as a stable, protected boronic ester reagent for palladium-catalyzed carbon-carbon bond formation, enabling the construction of drug-like molecules.
• Medicinal Chemistry Research: Used in high-throughput screening and lead optimization libraries to explore new chemical space and develop novel therapeutic candidates.
• Agrochemical Synthesis: Employed in the development of new herbicides, fungicides, and insecticides that require specific fluorinated aromatic structures.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology Probes: Can be utilized to create tagged molecules for studying biological pathways and protein interactions.

Basic Information

Product Name	4-Fluoro-2-(Morpholinomethyl)Phenylboronic Acid Pinacol Ester Hydrochloride
CAS No.	2096340-34-8
Molecular Formula	C₁₇H₂₆BClFNO₃
Molecular Weight	357.65 g/mol
Synonyms	4-Fluoro-2-(morpholin-4-ylmethyl)phenylboronic acid pinacol ester hydrochloride; 2-(4-Fluoro-2-(morpholinomethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane hydrochloride; (4-Fluoro-2-((morpholin-4-yl)methyl)phenyl)boronic acid pinacol ester hydrochloride; Pinacol [4-fluoro-2-(morpholin-4-ylmethyl)phenyl]boronate hydrochloride; CAS 2096340-34-8; Boronic ester intermediate 2096340-34-8
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, NMR, and HPLC are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Typical: 97-99%)
Water Content (KF)	≤1.0%
Heavy Metals	<20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.