Description

n-(3-Fluoro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl)Cyclohexanamine is a high-purity, advanced pharmaceutical intermediate featuring a pinacol boronate ester group, which is crucial for modern cross-coupling reactions like Suzuki-Miyaura. This compound matters because it enables the efficient synthesis of complex, fluorinated bioactive molecules, offering researchers and manufacturers a reliable building block for drug discovery and development. It is primarily needed by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers focused on creating new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reactions: The pinacol boronate ester moiety enables efficient carbon-carbon bond formation with aryl halides, a cornerstone of modern medicinal chemistry.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require fluorinated aromatic structures.
• Material Science: Serves as a precursor for creating functionalized organic molecules used in organic light-emitting diodes (OLEDs) and liquid crystals.
• Chemical Biology & Proteomics: Employed as a tool compound or linker for developing chemical probes and bioconjugation strategies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting outsourced drug discovery and process development projects.

Basic Information

Product Name	n-(3-Fluoro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl)Cyclohexanamine
CAS No.	2096340-18-8
Molecular Formula	C19H29BFNO2
Molecular Weight	341.25 g/mol
Synonyms	N-[(3-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methyl]cyclohexanamine; Cyclohexanamine, N-[[3-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl]-; 3-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzylcyclohexylamine; (3-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanamine, N-cyclohexyl-; 2096340-18-8; Boronic acid, B-[4-[[(cyclohexylamino)methyl]-2-fluorophenyl]-, 4,4,5,5-tetramethyl-1,3,2-dioxaborolane ester
EINECS	Contact for details

Quality Control

Our n-(3-Fluoro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl)Cyclohexanamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support compliance with ICH Q7 guidelines for active pharmaceutical ingredients (APIs) and intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Keep away from heat, sparks, and open flame. Due to its sensitivity to light and oxidation, prolonged exposure to air and light should be avoided.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.