Description

[3-(Benzyloxy)-5-Chloro-4-Fluorophenyl]Boronic Acid is a high-purity, synthetically valuable organoboron building block. This compound is essential for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for constructing complex biaryl and heterobiaryl structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex aromatic scaffolds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific halogenated biaryl motifs.
• Material Science Research: Serves as a monomer or building block for creating advanced organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis or as a core structure in catalyst design.
• Chemical Biology & Probe Synthesis: Useful for constructing molecular probes and bioconjugates for target identification and biochemical assay development.

Basic Information

Product Name	[3-(Benzyloxy)-5-Chloro-4-Fluorophenyl]Boronic Acid
CAS No.	2096340-14-4
Molecular Formula	C₁₃H₁₁BClFO₃
Molecular Weight	279.49 g/mol
Synonyms	(3-(Benzyloxy)-5-chloro-4-fluorophenyl)boronic acid; 5-Chloro-4-fluoro-3-(phenylmethoxy)benzeneboronic acid; (5-Chloro-4-fluoro-3-(benzyloxy)phenyl)boronic acid; Boronic acid, B-[3-(benzyloxy)-5-chloro-4-fluorophenyl]-; 2096340-14-4; 3-Benzyloxy-5-chloro-4-fluorobenzeneboronic acid
EINECS	Contact for details

Quality Control

Our [3-(Benzyloxy)-5-Chloro-4-Fluorophenyl]Boronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with global regulatory frameworks, including REACH and ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.