Description

4-Benzyloxy-3-Chloro-5-Fluorobenzeneboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those containing complex fluorinated and chlorinated aromatic systems.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides with tailored properties.
• Material Science Research: Serves as a monomer or building block for creating specialized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Probe Development: Utilized in the creation of molecular probes and sensors due to its specific reactivity and potential for bioconjugation.
• Academic & Industrial R&D: A fundamental reagent for method development and exploring new catalytic processes in organic synthesis laboratories worldwide.

Basic Information

Product Name	4-Benzyloxy-3-Chloro-5-Fluorobenzeneboronic Acid
CAS No.	2096340-08-6
Molecular Formula	C₁₃H₁₁BClFO₃
Molecular Weight	279.49 g/mol
Synonyms	3-Chloro-5-fluoro-4-(phenylmethoxy)benzeneboronic acid; (3-Chloro-5-fluoro-4-(benzyloxy)phenyl)boronic acid; 4-(Benzyloxy)-3-chloro-5-fluorobenzeneboronic Acid; B-(3-Chloro-5-fluoro-4-(phenylmethoxy)phenyl)boronic acid; 2096340-08-6
EINECS	Contact for details

Quality Control

Our 4-Benzyloxy-3-Chloro-5-Fluorobenzeneboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive coupling reactions. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.