Description

2,4-Difluoro-3-Isopropoxy-5-Methylphenylboronic Acid is a high-value, multi-functional boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing drug candidates, particularly in medicinal chemistry programs targeting new therapeutics.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the difluoro and isopropoxy substituents contribute to specific biological activity.
• Material Science Research: Employed in the creation of organic electronic materials, such as novel polymers or small molecules for OLEDs, where precise molecular structure is crucial.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands or organoboron catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A vital component for CROs and CDMOs offering bespoke chemical synthesis services to global clients.

Basic Information

Product Name	2,4-Difluoro-3-Isopropoxy-5-Methylphenylboronic Acid
CAS No.	2096339-90-9
Molecular Formula	C10H13BF2O3
Molecular Weight	230.02 g/mol
Synonyms	(2,4-Difluoro-3-isopropoxy-5-methylphenyl)boronic acid; 3-Isopropoxy-2,4-difluoro-5-methylbenzeneboronic acid; 2,4-Difluoro-3-(1-methylethoxy)-5-methylbenzeneboronic acid; Boronic acid, B-(2,4-difluoro-3-isopropoxy-5-methylphenyl)-; 5-Methyl-2,4-difluoro-3-isopropoxyphenylboronic acid; CAS 2096339-90-9
EINECS	Contact for details

Quality Control

Every batch of 2,4-Difluoro-3-Isopropoxy-5-Methylphenylboronic Acid is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, NMR, and LC-MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment, supporting cGMP and ISO standards for traceability and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry place. This material is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.