Description

3-Chloro-5-Ethoxy-4-Fluorophenylboronic Acid is a high-purity, multi-functional boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to create advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand & Catalyst Development: Employed in the research and production of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Material Science Research: Serves as a monomer or functionalization agent in the development of organic electronic materials, such as OLEDs and semiconductors.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs serving the global life sciences market.

Basic Information

Product Name	3-Chloro-5-Ethoxy-4-Fluorophenylboronic Acid
CAS No.	2096339-86-3
Molecular Formula	C8H9BClFO3
Molecular Weight	217.42 g/mol
Synonyms	(3-Chloro-5-ethoxy-4-fluorophenyl)boronic acid; 3-Chloro-5-ethoxy-4-fluorobenzeneboronic acid; 3-Chloro-4-fluoro-5-ethoxyphenylboronic acid; Boronic acid, B-(3-chloro-5-ethoxy-4-fluorophenyl)-; 2096339-86-3; 3-Cl-5-EtO-4-F-C6H2B(OH)2; 5-Ethoxy-3-chloro-4-fluorophenylboronic acid
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-5-Ethoxy-4-Fluorophenylboronic Acid is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Assay (NMR)	≥95.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.