Description

Boronic Acid, B-[2-Fluoro-6-Methoxy-3-(Trifluoromethyl)Phenyl]- is a high-value, multi-functional organoboron building block characterized by its unique trifluoromethyl and methoxy-substituted aromatic ring. This compound is essential for modern synthetic chemistry, particularly in cross-coupling reactions like the Suzuki-Miyaura reaction, due to its stability and reactivity profile. It is primarily sought after by research institutions and pharmaceutical companies for the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides with enhanced efficacy and environmental profiles.
• Material Science: Serves as a precursor for creating functional polymers, liquid crystals, and organic electronic materials.
• Suzuki-Miyaura Cross-Coupling: A key reagent for forming carbon-carbon bonds to construct biaryl structures, a common motif in medicinal chemistry.
• Chemical Biology & Proteomics: Utilized in the design of molecular probes and inhibitors for studying enzyme function and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and process development.

Basic Information

Product Name	Boronic Acid, B-[2-Fluoro-6-Methoxy-3-(Trifluoromethyl)Phenyl]-
CAS No.	2096339-77-2
Molecular Formula	C9H7BF4O3
Molecular Weight	249.96 g/mol
Synonyms	(2-Fluoro-6-methoxy-3-(trifluoromethyl)phenyl)boronic acid; 2-Fluoro-6-methoxy-3-(trifluoromethyl)benzeneboronic acid; B-(2-Fluoro-6-methoxy-3-(trifluoromethyl)phenyl)boronic acid; 2-Fluoro-6-methoxy-α,α,α-trifluoro-m-tolylboronic acid; [2-Fluoro-6-methoxy-3-(trifluoromethyl)phenyl]boronic acid
EINECS	Contact for details

Quality Control

Our production of Boronic Acid, B-[2-Fluoro-6-Methoxy-3-(Trifluoromethyl)Phenyl]- adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive applications. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.