Description

5-Bromo-2,3-Difluorophenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly in the development of active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those containing difluorinated and brominated aromatic systems.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers, liquid crystals, and organic electronic materials.
• Suzuki-Miyaura Cross-Coupling: The primary application is as a versatile boronic acid coupling partner for palladium-catalyzed reactions with aryl halides.
• Chemical Research & Development: An invaluable tool for medicinal chemists and process chemists in lead optimization and route scouting.
• Ligand Synthesis: Can be utilized to create sophisticated ligands for catalysis and molecular recognition applications.

Basic Information

Item	Details
Product Name	5-Bromo-2,3-Difluorophenylboronic Acid
CAS No.	2096339-65-8
Molecular Formula	C6H4BBrF2O2
Molecular Weight	236.81 g/mol
Synonyms	5-Bromo-2,3-difluorobenzeneboronic acid; (5-Bromo-2,3-difluorophenyl)boronic acid; 2,3-Difluoro-5-bromophenylboronic acid; Boronic acid, B-(5-bromo-2,3-difluorophenyl)-; 2096339-65-8; 5-Br-2,3-F2PhB(OH)2
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-2,3-Difluorophenylboronic Acid is manufactured and tested under a strict quality management system. We guarantee high chemical purity and lot-to-lot consistency, which is critical for reproducible cross-coupling reactions. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles (including palladium content) is provided with each shipment to ensure it meets your specific R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under inert atmosphere (argon/nitrogen) for long-term storage to maintain stability and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (NMR)	Conforms
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.