Description

3-Butoxy-4-Fluoro-5-(Trifluoromethyl)Phenylboronic Acid is a high-value, multi-functional boronic acid derivative designed for advanced synthetic chemistry. Its unique structure, featuring both alkoxy and fluoro/trifluoromethyl substituents, makes it a critical building block for constructing complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine atoms for enhanced bioactivity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Acts as a handle for bioconjugation and the development of chemical probes and inhibitors targeting specific enzymes or proteins.
• Catalyst & Ligand Development: Utilized in the synthesis of novel organoboron-based catalysts and ligands for asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	3-Butoxy-4-Fluoro-5-(Trifluoromethyl)Phenylboronic Acid
CAS No.	2096339-47-6
Molecular Formula	C₁₁H₁₃BF₄O₃
Molecular Weight	280.03 g/mol
Synonyms	3-Butoxy-4-fluoro-5-(trifluoromethyl)benzeneboronic acid; (3-Butoxy-4-fluoro-5-(trifluoromethyl)phenyl)boronic acid; 4-Fluoro-3-butoxy-5-(trifluoromethyl)phenylboronic acid; B-[3-Butoxy-4-fluoro-5-(trifluoromethyl)phenyl]boronic acid; 2096339-47-6; Boronic acid, B-[3-butoxy-4-fluoro-5-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Every batch of 3-Butoxy-4-Fluoro-5-(Trifluoromethyl)Phenylboronic Acid is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We guarantee high purity and lot-to-lot consistency to meet the stringent requirements of research and cGMP manufacturing. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.