Description

3-Chloro-4-Isopropoxy-5-Isobutoxyphenylboronic Acid is a high-purity, multi-functionalized phenylboronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its value lies in its dual alkoxy-substituted aromatic structure, which provides enhanced solubility and steric tuning for precise cross-coupling reactions. This advanced intermediate is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific aryl-aryl bond formations.
• Ligand & Catalyst Development: Serves as a starting material for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Building block for synthesizing organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and sensors that leverage boronic acid-diol interactions.
• Custom Synthesis & Contract Manufacturing: Essential for custom synthesis houses and CROs/CMOs developing proprietary compounds for clients.

Basic Information

Item	Details
Product Name	3-Chloro-4-Isopropoxy-5-Isobutoxyphenylboronic Acid
CAS No.	2096339-27-2
Molecular Formula	C13H20BClO3
Molecular Weight	270.56 g/mol
Synonyms	(3-Chloro-4-isopropoxy-5-isobutoxyphenyl)boronic acid; 3-Chloro-4-(propan-2-yloxy)-5-(2-methylpropoxy)benzeneboronic acid; Boronic acid, B-[3-chloro-4-(1-methylethoxy)-5-(2-methylpropoxy)phenyl]-; 3-Chloro-4-isopropoxy-5-isobutoxybenzeneboronic acid; 2096339-27-2 (CAS); Multi-alkoxy phenylboronic acid derivative
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Isopropoxy-5-Isobutoxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (NMR)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.