Description

3,5-Difluoro-2-Methyl-4-Propoxyphenylboronic Acid is a high-purity, multi-functional boronic acid derivative essential for modern synthetic chemistry. Its primary value lies as a versatile building block in cross-coupling reactions, enabling the precise construction of complex molecular architectures. This compound is critically needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to construct complex heterocyclic scaffolds found in advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or functionalization agent in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Employed in the synthesis of activity-based probes and affinity ligands for studying enzyme function and protein interactions.
• Ligand & Catalyst Development: Acts as a starting material for creating sophisticated chiral ligands and organometallic catalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A critical raw material for CROs and CDMOs producing bespoke compounds for client projects under cGMP or research-grade conditions.

Basic Information

Product Name	3,5-Difluoro-2-Methyl-4-Propoxyphenylboronic Acid
CAS No.	2096339-21-6
Molecular Formula	C₁₀H₁₃BF₂O₃
Molecular Weight	230.02 g/mol
Synonyms	4-Propoxy-3,5-difluoro-2-methylbenzeneboronic acid; (3,5-Difluoro-2-methyl-4-propoxyphenyl)boronic acid; 2-Methyl-3,5-difluoro-4-propoxybenzeneboronic acid; Boronic acid, B-(3,5-difluoro-2-methyl-4-propoxyphenyl)-; 2096339-21-6; 3,5-Difluoro-2-methyl-4-propoxybenzeneboronic acid
EINECS	Contact for details

Quality Control

Every batch of 3,5-Difluoro-2-Methyl-4-Propoxyphenylboronic Acid is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent internal specifications, which are aligned with industry best practices for advanced pharmaceutical intermediates. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.