Description

Bis-(2-Methoxy-Ethyl)-[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Benzyl]-Amine is a high-value, functionalized organoboron building block featuring a protected boronic ester group and a tertiary amine moiety. This compound is critical for facilitating Suzuki-Miyaura cross-coupling reactions in complex molecule synthesis, offering enhanced solubility and stability in organic media. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel chemical entities and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides by introducing the benzyl-amine-boronate functional group into target molecules.
• Material Science & OLED Development: Serves as a building block for synthesizing organic semiconductors, light-emitting materials, and other functional polymers.
• Ligand & Catalyst Design: The tertiary amine group can be utilized to develop novel ligands for metal catalysis or functionalize surfaces and nanoparticles.
• Chemical Biology & Probe Synthesis: Employed in creating molecular probes and bioconjugates for diagnostic and research applications.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for custom synthesis houses serving the life sciences and specialty chemicals industries.

Basic Information

Product Name	Bis-(2-Methoxy-Ethyl)-[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Benzyl]-Amine
CAS No.	2096339-20-5
Molecular Formula	C21H36BNO5
Molecular Weight	393.33 g/mol
Synonyms	2-[4-[[Bis(2-methoxyethyl)amino]methyl]phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-[[Bis(2-methoxyethyl)amino]methyl]benzeneboronic acid pinacol ester; [4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl]bis(2-methoxyethyl)amine; N,N-Bis(2-methoxyethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenemethanamine; Boronic ester amine derivative; Pinacol boronate amine.
EINECS	Contact for details

Quality Control

Our Bis-(2-Methoxy-Ethyl)-[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Benzyl]-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP or research-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.