Description

3-Chloro-4-Fluoro-5-(2-Methoxyethoxy)Phenylboronic Acid is a high-purity, multi-functional boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily sought after by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and oncology research.
• Agrochemical Synthesis: Used to construct complex heterocyclic scaffolds found in modern herbicides, fungicides, and plant growth regulators.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and OFETs, due to its functionalized aromatic core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized boronate esters and other ligands used in asymmetric catalysis.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: A vital component for CROs and CDMOs engaged in custom synthesis projects requiring specific aryl boronic acid functionalities.

Basic Information

Product Name	3-Chloro-4-Fluoro-5-(2-Methoxyethoxy)Phenylboronic Acid
CAS No.	2096338-69-9
Molecular Formula	C9H11BClFO4
Molecular Weight	247.44 g/mol
Synonyms	[3-Chloro-4-fluoro-5-(2-methoxyethoxy)phenyl]boronic acid; 3-Chloro-4-fluoro-5-(2-methoxyethoxy)benzeneboronic acid; 5-(2-Methoxyethoxy)-3-chloro-4-fluorophenylboronic acid; Boronic acid, B-[3-chloro-4-fluoro-5-(2-methoxyethoxy)phenyl]-; CAS 2096338-69-9
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Fluoro-5-(2-Methoxyethoxy)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with relevant regulatory frameworks for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Heavy Metals	<20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.