Description

4-Butoxy-3-Chloro-5-Fluorophenylboronic Acid is a high-purity, synthetically valuable boronic acid derivative, serving as a critical building block in modern organic synthesis. Its primary value lies in enabling the precise construction of complex molecules through reliable cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides with tailored properties.
• Liquid Crystal & OLED Material Development: Acts as a building block for creating complex organic frameworks used in electronic displays and lighting.
• Polymer Chemistry: Employed to introduce functional aryl groups into polymer backbones, modifying material properties like thermal stability and solubility.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D labs exploring new catalytic processes and organic transformations.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke, high-value compounds for client projects.

Basic Information

Product Name	4-Butoxy-3-Chloro-5-Fluorophenylboronic Acid
CAS No.	2096338-35-9
Molecular Formula	C₁₀H₁₃BClFO₃
Molecular Weight	246.47 g/mol
Synonyms	(4-Butoxy-3-chloro-5-fluorophenyl)boronic acid; 3-Chloro-5-fluoro-4-butoxyphenylboronic acid; 4-Butoxy-3-chloro-5-fluorobenzeneboronic acid; Boronic acid, B-(4-butoxy-3-chloro-5-fluorophenyl)-; 2096338-35-9; 4-n-Butoxy-3-chloro-5-fluorophenylboronic acid
EINECS	Contact for details

Quality Control

Every batch of 4-Butoxy-3-Chloro-5-Fluorophenylboronic Acid is produced and tested under strict quality management protocols to ensure consistency and reliability for your critical syntheses. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity (by HPLC/NMR), identity confirmation, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.