Description

3-(Benzyloxy)-2-Fluoro-5-Methylphenylboronic Acid is a specialized organoboron compound serving as a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients, particularly for applications requiring specific fluorinated and substituted aromatic scaffolds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates containing fluorinated biphenyl or terphenyl motifs.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides where the specific substitution pattern can influence biological activity.
• Material Science Research: Serves as a monomer or building block for creating novel organic electronic materials, such as those used in OLEDs or organic semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of sophisticated ligands for catalysis or as a core structure in metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems and drug-target interactions.
• Custom Synthesis and Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3-(Benzyloxy)-2-Fluoro-5-Methylphenylboronic Acid
CAS No.	2096338-26-8
Molecular Formula	C14H14BFO3
Molecular Weight	260.07 g/mol
Synonyms	(3-(Benzyloxy)-2-fluoro-5-methylphenyl)boronic acid; 2-Fluoro-5-methyl-3-(phenylmethoxy)benzeneboronic acid; 3-Benzyloxy-2-fluoro-5-methylbenzeneboronic acid; B-[3-(Benzyloxy)-2-fluoro-5-methylphenyl]boronic acid; (2-Fluoro-3-benzyloxy-5-methylphenyl)boronic acid; 2096338-26-8; Boronic acid, B-[3-(benzyloxy)-2-fluoro-5-methylphenyl]-
EINECS	Contact for details

Quality Control

Our production of 3-(Benzyloxy)-2-Fluoro-5-Methylphenylboronic Acid adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity, typically exceeding 97% (HPLC). Each lot is fully characterized and accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support development and production needs across various standards, including cGMP for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.