Description

2,6-Difluoro-4-Isopropyloxyphenylboronic Acid is a high-value organoboron building block essential for modern synthetic chemistry. This compound matters as a key intermediate in the Suzuki-Miyaura cross-coupling reaction, enabling the efficient construction of complex biaryl structures. It is primarily needed by pharmaceutical R&D teams and agrochemical manufacturers for creating novel active ingredients, as well as by material scientists developing advanced organic electronic materials.

Application

• Pharmaceutical Intermediate: Critical for synthesizing active pharmaceutical ingredients (APIs) with complex diaryl or heterobiaryl motifs, particularly in oncology and CNS drug discovery.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides that require specific fluorinated aromatic systems for enhanced activity and environmental profile.
• Material Science Research: Serves as a precursor for constructing organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) where the difluoro and isopropoxy substituents tune electronic and steric properties.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for studying biological pathways and target engagement.
• Catalyst Ligand Development: Utilized to create novel bidentate or monodentate ligands for transition metal catalysis, leveraging the boronic acid functionality.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific projects requiring precise, high-purity boronic acid derivatives.

Basic Information

Product Name	2,6-Difluoro-4-Isopropyloxyphenylboronic Acid
CAS No.	2096337-66-3
Molecular Formula	C9H11BF2O3
Molecular Weight	216.00 g/mol
Synonyms	(2,6-Difluoro-4-isopropoxyphenyl)boronic acid; 4-Isopropoxy-2,6-difluorophenylboronic acid; 2,6-Difluoro-4-(1-methylethoxy)benzeneboronic acid; Boronic acid, B-(2,6-difluoro-4-isopropoxyphenyl)-; 2,6-Difluoro-4-isopropoxybenzeneboronic acid; 4-(Isopropyloxy)-2,6-difluorophenylboronic acid
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-4-Isopropyloxyphenylboronic Acid is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with stringent industry standards for advanced intermediates. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.