Description

5-Bromo-2,3-difluoro-4-methoxyphenylboronic acid is a high-purity, multi-functional boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting complex heterocycles.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the difluoro and bromo substituents impart unique biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a versatile scaffold for constructing sophisticated ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those for OLEDs and semiconductors, where precise molecular engineering is required.
• Chemical Biology Probes: Useful for creating tagged molecules and activity-based probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	5-Bromo-2,3-difluoro-4-methoxyphenylboronic Acid
CAS No.	2096337-64-1
Molecular Formula	C7H6BBrF2O3
Molecular Weight	266.84 g/mol
Synonyms	(5-Bromo-2,3-difluoro-4-methoxyphenyl)boronic acid; 5-Bromo-2,3-difluoro-4-methoxybenzeneboronic acid; B-(5-Bromo-2,3-difluoro-4-methoxyphenyl)boronic acid; 2,3-Difluoro-5-bromo-4-methoxybenzeneboronic acid; 4-Methoxy-5-bromo-2,3-difluorophenylboronic acid; 2096337-64-1; Boronic acid, B-(5-bromo-2,3-difluoro-4-methoxyphenyl)-
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-2,3-difluoro-4-methoxyphenylboronic acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is available for each lot, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the original container sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.