Description

2-Ethoxy-4-Fluoro-5-Methylphenylboronic Acid is a specialized organoboron compound that serves as a crucial building block in modern synthetic chemistry. Its value lies in its role as a key intermediate for constructing complex molecular architectures via cross-coupling reactions, enabling the development of novel materials and active pharmaceutical ingredients. This high-purity boronic acid is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for process development and scale-up.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting complex biaryl structures.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the introduction of the ethoxy-fluoro-methylphenyl moiety can enhance biological activity and selectivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organometallic catalysts used in asymmetric synthesis and other catalytic processes.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those for OLEDs or organic semiconductors, where precise molecular engineering is required.
• Chemical Biology Probes: Utilized in the construction of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A critical reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Product Name	2-Ethoxy-4-Fluoro-5-Methylphenylboronic Acid
CAS No.	2096337-59-4
Molecular Formula	C9H12BFO3
Molecular Weight	197.99 g/mol
Synonyms	(2-Ethoxy-4-fluoro-5-methylphenyl)boronic acid; 4-Fluoro-2-ethoxy-5-methylbenzeneboronic acid; 2-Ethoxy-4-fluoro-5-methylbenzeneboronic acid; Boronic acid, B-(2-ethoxy-4-fluoro-5-methylphenyl)-; 2096337-59-4; 5-Methyl-2-ethoxy-4-fluorophenylboronic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Ethoxy-4-Fluoro-5-Methylphenylboronic Acid is manufactured under strict quality management protocols. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specification parameters is provided with each shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry place. This material is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.