Description

3-Ethoxy-2,4-Difluoro-5-Methylphenylboronic Acid is a specialized organoboron compound belonging to the class of arylboronic acids. It serves as a critical synthetic intermediate, prized for its role in facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern organic synthesis. This high-purity building block is essential for researchers and manufacturers in the pharmaceutical and advanced materials sectors, enabling the efficient construction of complex molecular architectures for active pharmaceutical ingredients (APIs) and functional organic compounds.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in constructing complex biaryl and heterobiaryl structures common in modern therapeutics.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging the unique properties imparted by the ethoxy and difluoro substituents.
• Material Science: Employed in the synthesis of organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and semiconductors, where precise molecular design is crucial.
• Chemical Synthesis: Acts as a versatile reagent in Suzuki-Miyaura cross-coupling reactions for carbon-carbon bond formation in academic and industrial R&D laboratories.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Life Sciences & Diagnostics: Potential use in the development of molecular probes and sensors due to the boronic acid group's ability to bind with diols and other biological targets.

Basic Information

Product Name	3-Ethoxy-2,4-Difluoro-5-Methylphenylboronic Acid
CAS No.	2096336-30-8
Molecular Formula	C9H11BF2O3
Molecular Weight	216.00 g/mol
Synonyms	(3-Ethoxy-2,4-difluoro-5-methylphenyl)boronic acid; 2,4-Difluoro-3-ethoxy-5-methylbenzeneboronic acid; 5-Methyl-3-ethoxy-2,4-difluorophenylboronic acid; Boronic acid, B-(3-ethoxy-2,4-difluoro-5-methylphenyl)-; 2096336-30-8; 3-Ethoxy-2,4-difluoro-5-methyl-benzeneboronic acid
EINECS	Contact for details

Quality Control

Our 3-Ethoxy-2,4-Difluoro-5-Methylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.