Description

4-(Cyclopentyloxy)-3,5-Difluoro-2-Methylphenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its role as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing a difluorinated biphenyl or heterobiaryl core.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific, sterically hindered biaryl motifs.
• Material Science Research: Serves as a monomer or building block for creating novel organic electronic materials, such as those used in OLEDs or organic semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis or as a scaffold for boron-based sensor molecules.
• Chemical Biology & Proteomics: Utilized in the development of chemical probes and affinity reagents that target specific proteins or enzymes.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	4-(Cyclopentyloxy)-3,5-Difluoro-2-Methylphenylboronic Acid
CAS No.	2096336-27-3
Molecular Formula	C₁₃H₁₇BF₂O₃
Molecular Weight	270.08 g/mol
Synonyms	2-Methyl-3,5-difluoro-4-(cyclopentyloxy)benzeneboronic acid; (4-Cyclopentyloxy-3,5-difluoro-2-methylphenyl)boronic acid; 3,5-Difluoro-2-methyl-4-(cyclopentyloxy)phenylboronic acid; B-[4-(Cyclopentyloxy)-3,5-difluoro-2-methylphenyl]boronic acid; 4-Cyclopentyloxy-3,5-difluoro-o-tolylboronic acid
EINECS	Contact for details

Quality Control

Our 4-(Cyclopentyloxy)-3,5-Difluoro-2-Methylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.