Description

6-Ethoxy-2-Fluoro-3-(Trifluoromethyl)Phenylboronic Acid is a high-value, multi-functional boronic acid derivative essential for modern synthetic chemistry. Its core value lies in its role as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is critically needed by R&D and process development teams in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing active pharmaceutical ingredients (APIs), particularly those containing complex fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific fluorinated phenyl motifs.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid reagent for palladium-catalyzed C-C bond formation to create biaryl and heterobiaryl compounds.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Material Science Research: A precursor for creating organic electronic materials, such as those used in OLEDs and semiconductors, where fluorine substitution tunes electronic properties.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes.

Basic Information

Item	Details
Product Name	6-Ethoxy-2-Fluoro-3-(Trifluoromethyl)Phenylboronic Acid
CAS No.	2096336-22-8
Molecular Formula	C10H11BF4O3
Molecular Weight	266.00 g/mol
Synonyms	2-Fluoro-6-ethoxy-3-(trifluoromethyl)benzeneboronic acid; [2-Fluoro-6-ethoxy-3-(trifluoromethyl)phenyl]boronic acid; 6-Ethoxy-2-fluoro-3-trifluoromethylbenzeneboronic acid; Boronic acid, B-[2-fluoro-6-ethoxy-3-(trifluoromethyl)phenyl]-; 2-Fluoro-6-ethoxy-α,α,α-trifluoro-m-tolylboronic acid
EINECS	Contact for details

Quality Control

Our 6-Ethoxy-2-Fluoro-3-(Trifluoromethyl)Phenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.