Description

2-Fluoro-3-Isopropoxy-5-Methylphenylboronic Acid is a high-purity, synthetically valuable organoboron building block. This compound is essential for modern cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in medicinal chemistry research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its unique fluorinated and alkoxy-substituted aromatic structure.
• Material Science Research: Serves as a building block for creating functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Employed in the synthesis of tagged molecules and probes for studying biological pathways and target engagement.
• Catalyst Ligand Development: Can be utilized to synthesize novel ligands for transition metal catalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	2-Fluoro-3-Isopropoxy-5-Methylphenylboronic Acid
CAS No.	2096336-18-2
Molecular Formula	C10H14BFO3
Molecular Weight	212.03 g/mol
Synonyms	(2-Fluoro-3-isopropoxy-5-methylphenyl)boronic acid; 2-Fluoro-3-isopropoxy-5-methylbenzeneboronic acid; 2-Fluoro-3-(1-methylethoxy)-5-methylbenzeneboronic acid; Boronic acid, B-(2-fluoro-3-isopropoxy-5-methylphenyl)-; 2096336-18-2; 2-Fluoro-3-isopropoxy-5-methylphenyl-B(OH)2
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-Isopropoxy-5-Methylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and oxidizable nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.