Description

1-(4-Fluoro-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl)Piperidine is a high-purity boronic ester derivative, a critical building block in modern synthetic chemistry. Its value lies in enabling efficient and selective cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This advanced intermediate is essential for research and development teams in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in CNS and oncology research.
• Agrochemical Synthesis: Used to construct complex heterocyclic structures found in advanced pesticides and herbicides.
• Material Science Research: Serves as a monomer or functionalization agent in the development of organic electronic materials and polymers.
• Chemical Biology Probes: Employed in the synthesis of tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring specific fluorinated and piperidine-containing motifs.

Basic Information

Product Name	1-(4-Fluoro-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl)Piperidine
CAS No.	2096335-83-8
Molecular Formula	C18H27BFNO2
Molecular Weight	319.23 g/mol
Synonyms	1-[(4-Fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methyl]piperidine; 1-((4-Fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)piperidine; 4-Fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzylpiperidine; 2-(2-Fluoro-5-(piperidin-1-ylmethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol (4-Fluoro-3-(piperidin-1-ylmethyl)phenyl)boronate
EINECS	Contact for details

Quality Control

Our production of 1-(4-Fluoro-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl)Piperidine adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity. All material is characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.