Description

6-Ethoxy-2-Fluoropyridine-3-Boronic Acid is a high-value boronic acid derivative and a key synthetic intermediate in modern organic chemistry. Its molecular structure, featuring both a fluorine substituent and a boronic acid functional group, makes it an essential building block for constructing complex heterocyclic systems. This compound is primarily utilized by research scientists and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic acid coupling partner for the formation of carbon-carbon bonds, enabling the construction of complex biaryl and heterobiaryl structures.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides, leveraging the pyridine core for bioactivity.
• Material Science Precursor: Employed in the synthesis of organic electronic materials, such as ligands for OLEDs or molecular sensors.
• Chemical Biology Probes: Facilitates the creation of tagged molecules and probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specialized boronic acid reagents.

Basic Information

Product Name	6-Ethoxy-2-Fluoropyridine-3-Boronic Acid
CAS No.	2096335-58-7
Molecular Formula	C7H9BFNO3
Molecular Weight	184.96 g/mol
Synonyms	(6-Ethoxy-2-fluoropyridin-3-yl)boronic acid; 2-Fluoro-6-ethoxypyridine-3-boronic acid; 3-Borono-6-ethoxy-2-fluoropyridine; 6-Ethoxy-2-fluoro-3-pyridineboronic acid; 2096335-58-7; AKOS026713004; BRN 17175745
EINECS	Contact for details

Quality Control

Our 6-Ethoxy-2-Fluoropyridine-3-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (NMR)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.