Description

3-Bromo-5-T-Butyl-2-Fluorophenylboronic Acid is a high-purity, multi-functional boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand & Catalyst Development: Serves as a starting material for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as OLED (Organic Light-Emitting Diode) components and conductive polymers.
• Chemical Biology Probes: Facilitates the creation of boronic acid-based probes and sensors for detecting biological analytes like sugars and peroxides.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific aryl boronic acid derivatives.

Basic Information

Item	Details
Product Name	3-Bromo-5-T-Butyl-2-Fluorophenylboronic Acid
CAS No.	2096333-35-4
Molecular Formula	C₁₀H₁₃BBrFO₂
Molecular Weight	274.93 g/mol
Synonyms	3-Bromo-5-tert-butyl-2-fluorobenzeneboronic acid; (3-Bromo-5-tert-butyl-2-fluorophenyl)boronic acid; 2-Fluoro-3-bromo-5-tert-butylphenylboronic acid; 3-Bromo-5-(tert-butyl)-2-fluorophenylboronic acid; Boronic acid, B-(3-bromo-5-(1,1-dimethylethyl)-2-fluorophenyl)-; 2096333-35-4; 3-Bromo-5-t-butyl-2-fluorophenylboronic acid
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-5-T-Butyl-2-Fluorophenylboronic Acid is manufactured under strict quality management systems. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed results from HPLC, NMR, and mass spectrometry to verify identity, purity, and consistency. Our quality commitment ensures the material meets the stringent requirements for research and development as well as scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.