Description

4-Borono-2,3-Difluorobenzotrifluoride is a high-value, multi-functional organoboron building block essential for modern synthetic chemistry. Its unique structure, combining a boronic acid pinacol ester moiety with fluorine and trifluoromethyl substituents, makes it a critical reagent for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in cross-coupling reactions, material science, and the development of novel active ingredients. CAS No. 2096332-61-3.

Application

• Pharmaceutical Intermediate: A key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially fluorinated bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial labs for method development and exploring new chemical spaces in organofluorine and organoboron chemistry.
• Ligand and Catalyst Design: Utilized to synthesize novel ligands and catalysts for asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	4-Borono-2,3-Difluorobenzotrifluoride
CAS No.	2096332-61-3
Molecular Formula	C9H5BF5O2
Molecular Weight	254.94 g/mol
Synonyms	2,3-Difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzotrifluoride; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-difluorobenzotrifluoride; 2,3-Difluoro-α,α,α-trifluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)toluene; 4-Borono-2,3-difluorobenzotrifluoride Pinacol Ester; 2,3-Difluoro-4-(pinacolatoboryl)benzotrifluoride; (2,3-Difluoro-4-(trifluoromethyl)phenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Every batch of 4-Borono-2,3-Difluorobenzotrifluoride is produced and tested under strict quality management protocols to ensure consistency and reliability for your critical R&D and scale-up processes. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.