Description

4-(n-Cbz-n-Propylamino)Phenylboronic Acid, Pinacol Ester is a sophisticated, protected boronic ester building block designed for advanced organic synthesis. This compound matters for its role as a key intermediate in cross-coupling reactions, enabling the precise construction of complex molecules. It is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and oncology research.
• Agrochemical Synthesis: Used in the development of advanced crop protection agents and herbicides requiring specific aryl-aryl linkages.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as polymers for OLEDs and organic photovoltaics.
• Chemical Biology Probes: Employed in the synthesis of bioconjugates and probes for studying biological pathways and protein interactions.
• Process Chemistry & Scale-up: Provides a stable, storable boronate source for large-scale manufacturing processes in fine chemical production.
• Academic & R&D Laboratories: A valuable reagent for methodological development in synthetic organic chemistry and catalysis studies.

Basic Information

Product Name	4-(n-Cbz-n-Propylamino)Phenylboronic Acid, Pinacol Ester
CAS No.	2096332-60-2
Molecular Formula	C24H32BNO4
Molecular Weight	409.33 g/mol
Synonyms	4-(N-Cbz-N-Propylamino)Benzeneboronic Acid Pinacol Ester; 4-[(Benzyloxycarbonyl)(propyl)amino]phenylboronic Acid Pinacol Ester; 4-(N-Carbobenzoxy-N-propylamino)Phenylboronic Acid Pinacol Ester; 4-[N-(Benzyloxycarbonyl)-N-propylamino]Phenylboronic Acid Pinacol Ester; 4-(Cbz-Propylamino)Phenylboronic Acid Pinacol Ester; B-[4-[[(Phenylmethoxy)carbonyl]propylamino]phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (4-((((Benzyloxy)carbonyl)(propyl)amino)phenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Every batch of 4-(n-Cbz-n-Propylamino)Phenylboronic Acid, Pinacol Ester undergoes rigorous analytical testing to ensure identity, purity, and consistency suitable for research and development applications. Our quality commitment includes adherence to in-house specifications developed for advanced synthetic intermediates. A comprehensive Certificate of Analysis (COA) detailing purity (HPLC), identity (NMR, IR), and other critical parameters is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This compound is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere or in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.