Description

3-Butoxy-5-Chloro-4-Fluorophenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its role as a key intermediate in cross-coupling reactions, enabling the efficient construction of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and advanced materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A fundamental reagent for creating carbon-carbon bonds in the synthesis of biaryl structures, a common motif in pharmaceuticals and organic electronics.
• Pharmaceutical Intermediate: Serves as a crucial precursor in the research and production of novel active pharmaceutical ingredients (APIs), especially those containing complex halogenated aryl groups.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the specific substitution pattern can influence biological activity.
• Material Science Research: Employed in the synthesis of organic ligands for catalysts, monomers for specialty polymers, and components for organic light-emitting diodes (OLEDs).
• Chemical Biology & Medicinal Chemistry: Acts as a versatile handle for bioconjugation and the synthesis of molecular probes for drug discovery and diagnostic applications.

Basic Information

Product Name	3-Butoxy-5-Chloro-4-Fluorophenylboronic Acid
CAS No.	2096332-32-8
Molecular Formula	C₁₀H₁₃BClFO₃
Molecular Weight	246.47 g/mol
Synonyms	(3-Butoxy-5-chloro-4-fluorophenyl)boronic acid; 5-Chloro-4-fluoro-3-butoxybenzeneboronic acid; Boronic acid, B-(3-butoxy-5-chloro-4-fluorophenyl)-; 3-Chloro-4-fluoro-5-butoxyphenylboronic acid; CAS 2096332-32-8
EINECS	Contact for details

Quality Control

Our 3-Butoxy-5-Chloro-4-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage at 2-8°C. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.