Description

3-(2-Fluoroethoxy)Phenylboronic Acid is a high-purity, synthetically valuable boronic acid derivative. This compound matters as a critical building block in modern organic synthesis, particularly for cross-coupling reactions like the Suzuki-Miyaura reaction, enabling the efficient construction of complex molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional compounds. Its specific substitution pattern offers unique reactivity and physicochemical properties for targeted molecular design.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those requiring fluorinated aromatic systems.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the fluorinated phenylboronic acid moiety introduces favorable biological activity and metabolic stability.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, via polymerization or functionalization reactions.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile coupling partner with aryl/vinyl halides to form biaryl and styrenyl structures, a cornerstone reaction in medicinal and process chemistry.
• Ligand and Catalyst Development: Utilized for constructing complex ligands for transition metal catalysts or as a handle for bioconjugation in chemical biology.
• Chemical Library Production: A valuable reagent for combinatorial and parallel synthesis in high-throughput screening for drug discovery programs.

Basic Information

Item	Detail
Product Name	3-(2-Fluoroethoxy)Phenylboronic Acid
CAS No.	2096332-11-3
Molecular Formula	C8H10BFO3
Molecular Weight	183.98 g/mol
Synonyms	[3-(2-Fluoroethoxy)phenyl]boronic acid; 3-(2-Fluoroethoxy)benzeneboronic acid; (3-(2-Fluoroethoxy)phenyl)boronic acid; 2-Fluoroethoxy-3-phenylboronic acid; Boronic acid, B-[3-(2-fluoroethoxy)phenyl]-; 2096332-11-3; 3-Fluoroethoxyphenylboronic acid; 3-(2-Fluoroethoxy)phenyl-B(OH)2
EINECS	Contact for details

Quality Control

Our 3-(2-Fluoroethoxy)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request for every shipment, providing full traceability and batch-specific documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and reactivity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.