Description

2,5-Difluoro-4-Propoxyphenylboronic Acid is a high-purity organoboron compound, specifically a functionalized phenylboronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing difluorinated biphenyl or terphenyl scaffolds.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific fluorinated aromatic systems.
• Material Science: Building block for creating organic electronic materials, such as those used in OLEDs and semiconductors, where fluorine substitution tunes electronic properties.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A valuable reagent for medicinal chemistry programs and process chemistry optimization in both academic and industrial R&D laboratories.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals for various technological applications.

Basic Information

Product Name	2,5-Difluoro-4-Propoxyphenylboronic Acid
CAS No.	2096331-99-4
Molecular Formula	C9H11BF2O3
Molecular Weight	216.00 g/mol
Synonyms	(2,5-Difluoro-4-propoxyphenyl)boronic Acid; 4-Propoxy-2,5-difluorophenylboronic Acid; 2,5-Difluoro-4-propoxybenzeneboronic Acid; Boronic acid, B-(2,5-difluoro-4-propoxyphenyl)-; 2096331-99-4; 2,5-Difluoro-4-propoxy phenyl boronic acid
EINECS	Contact for details

Quality Control

Our 2,5-Difluoro-4-Propoxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This compound may be moisture-sensitive; therefore, it is recommended to handle and store it under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after opening the primary container.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Assay (NMR)	≥95.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.