Description

2,4-Difluoro-3-Methoxy-5-Methylphenylboronic Acid is a high-purity, multi-functional boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its value lies in enabling the precise construction of complex molecules through reliable cross-coupling reactions. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, where it is used to develop novel active ingredients and functional materials.

Application

This specialized boronic acid is a versatile reagent with key applications in several high-tech sectors:

• Pharmaceutical Intermediate: A crucial building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs), particularly in drug discovery for fluorinated compounds.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the difluoro and methoxy substituents can enhance biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating sophisticated ligands and organometallic catalysts used in asymmetric synthesis and other catalytic processes.
• Materials Science Research: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs or organic photovoltaics, where its structure can tune electronic properties.
• Chemical Biology & Probe Synthesis: Useful for creating fluorescent probes or bioconjugates for diagnostic and research applications, leveraging the boronic acid group's affinity for diols.

Basic Information

Product Name	2,4-Difluoro-3-Methoxy-5-Methylphenylboronic Acid
CAS No.	2096331-81-4
Molecular Formula	C8H9BF2O3
Molecular Weight	201.97 g/mol
Synonyms	(2,4-Difluoro-3-methoxy-5-methylphenyl)boronic acid; 2,4-Difluoro-3-methoxy-5-methylbenzeneboronic acid; 5-Methyl-2,4-difluoro-3-methoxyphenylboronic acid; Boronic acid, B-(2,4-difluoro-3-methoxy-5-methylphenyl)-; 2096331-81-4
EINECS	Contact for details

Quality Control

Our production of 2,4-Difluoro-3-Methoxy-5-Methylphenylboronic Acid adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and NMR for structural confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.