Description

3-Chloro-4-Fluoro-5-Isopropoxyphenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in its role as a key intermediate for constructing complex molecules via cross-coupling reactions, enabling the development of novel compounds. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries, particularly those focused on creating new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in kinase inhibitor and other small-molecule therapeutic development.
• Agrochemical Synthesis: Used to construct complex heterocyclic structures found in advanced herbicides, fungicides, and insecticides, contributing to crop protection solutions.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organometallic catalysts used in asymmetric synthesis and other catalytic processes.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those for OLEDs and organic semiconductors, where precise molecular architecture is required.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A key raw material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke organic compounds for client projects.

Basic Information

Product Name	3-Chloro-4-Fluoro-5-Isopropoxyphenylboronic Acid
CAS No.	2096331-77-8
Molecular Formula	C9H11BClFO3
Molecular Weight	231.45 g/mol
Synonyms	(3-Chloro-4-fluoro-5-isopropoxyphenyl)boronic acid; 3-Chloro-4-fluoro-5-(1-methylethoxy)benzeneboronic acid; 3-Chloro-4-fluoro-5-isopropoxybenzeneboronic acid; Boronic acid, B-(3-chloro-4-fluoro-5-isopropoxyphenyl)-; 2096331-77-8; 3-Cl-4-F-5-Isopropoxyphenylboronic Acid; 5-Isopropoxy-3-chloro-4-fluorophenylboronic acid
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Fluoro-5-Isopropoxyphenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance in demanding synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere or in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.