Description

2,4-Difluoro-5-Bromophenylboronic Acid is a high-purity, multi-functional boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the precise construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing complex drug candidates, especially those containing difluorinated and brominated aryl motifs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, leveraging its halogen and fluorine substituents for bioactivity.
• Material Science: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and enzyme inhibitors for target identification and validation studies.
• Ligand Synthesis: Useful for preparing specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects requiring specific aryl boronic acid functionality.

Basic Information

Product Name	2,4-Difluoro-5-Bromophenylboronic Acid
CAS No.	2096331-76-7
Molecular Formula	C6H4BBrF2O2
Molecular Weight	236.81 g/mol
Synonyms	(5-Bromo-2,4-difluorophenyl)boronic acid; 2,4-Difluoro-5-bromobenzeneboronic acid; 5-Bromo-2,4-difluorophenylboronic acid; B-(5-Bromo-2,4-difluorophenyl)boronic acid; 2096331-76-7; (5-Bromo-2,4-difluorophenyl)boronic acid pinacol ester (common derivative); 2,4-Difluoro-5-bromo phenyl boronic acid
EINECS	Contact for details

Quality Control

Every batch of 2,4-Difluoro-5-Bromophenylboronic Acid is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency. Our standard quality commitment includes comprehensive analysis via HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.