Description

2-Isobutoxy-4-(Trifluoromethyl)Phenylboronic Acid is a specialized organoboron compound, a key building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing trifluoromethyl-substituted biaryl motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific fluorinated aromatic systems.
• Material Science Research: Serves as a building block for creating novel organic electronic materials, such as those used in OLEDs and semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and other boron-based reagents.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.

Basic Information

Product Name	2-Isobutoxy-4-(Trifluoromethyl)Phenylboronic Acid
CAS No.	2096331-64-3
Molecular Formula	C11H14BF3O3
Molecular Weight	262.04 g/mol
Synonyms	[2-(2-Methylpropoxy)-4-(trifluoromethyl)phenyl]boronic acid; 4-Trifluoromethyl-2-isobutoxyphenylboronic acid; 2-Isobutoxy-4-trifluoromethylbenzeneboronic acid; (2-Isobutoxy-4-(trifluoromethyl)phenyl)boronic acid; Boronic acid, B-[2-(2-methylpropoxy)-4-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our 2-Isobutoxy-4-(Trifluoromethyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term stability and to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.