Description

2-(Benzyloxy)-4-Fluoro-5-Methylphenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in its role as a key intermediate for constructing complex molecules via cross-coupling reactions, enabling the development of advanced materials and pharmaceuticals. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to create novel, high-value products.

Application

• Pharmaceutical Intermediate: A crucial precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs), especially in oncology and CNS drug discovery.
• Agrochemical Synthesis: Used to construct complex heterocyclic structures found in advanced herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for transition metal catalysis and organocatalysis.
• Chemical Biology Probes: Utilized to create boronic acid-based probes for sensing, imaging, and protein labeling applications.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Item	Details
Product Name	2-(Benzyloxy)-4-Fluoro-5-Methylphenylboronic Acid
CAS No.	2096331-49-4
Molecular Formula	C14H14BFO3
Molecular Weight	260.07 g/mol
Synonyms	2-(Benzyloxy)-4-fluoro-5-methylbenzeneboronic acid; 4-Fluoro-5-methyl-2-(phenylmethoxy)benzeneboronic acid; (2-(Benzyloxy)-4-fluoro-5-methylphenyl)boronic acid; B-[2-(Benzyloxy)-4-fluoro-5-methylphenyl]boronic acid; 2096331-49-4; 2-Benzyloxy-4-fluoro-5-methylphenylboronic acid; Boronic acid, B-[2-(benzyloxy)-4-fluoro-5-methylphenyl]-
EINECS	Contact for details

Quality Control

Our 2-(Benzyloxy)-4-Fluoro-5-Methylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability for your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (NMR)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.