Description

Methyl 2-Bromo-5-Fluoro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate CAS NO 2096331-46-1 is a high-value, multi-functional boronic ester derivative designed for advanced synthetic chemistry. This compound is a critical building block for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing complex fluorinated and brominated aromatic systems.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides by introducing specific halogenated and boronate functional groups into lead structures.
• Material Science Research: Serves as a monomer or building block for constructing organic electronic materials, such as OLEDs, OFETs, and conductive polymers.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for imaging and diagnostic applications.
• Custom Synthesis and R&D: A versatile reagent for contract research organizations (CROs) and academic laboratories exploring new chemical spaces and reaction methodologies.

Basic Information

Product Name	Methyl 2-Bromo-5-Fluoro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate
CAS No.	2096331-46-1
Molecular Formula	C14H17BBrFO4
Molecular Weight	358.00 g/mol
Synonyms	2-Bromo-5-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid methyl ester; Methyl 2-bromo-5-fluoro-4-(pinacolatoboron)benzoate; 2-Bromo-5-fluoro-4-(pinacolboronato)benzoic acid methyl ester; 2096331-46-1; Benzoic acid, 2-bromo-5-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, methyl ester
EINECS	Contact for details

Quality Control

Every batch of Methyl 2-Bromo-5-Fluoro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoate is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for demanding R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry place. This compound is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.