Description

3,5-Difluoro-4-Propoxyphenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in its role as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing complex difluorinated biphenyl or terphenyl scaffolds.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific fluorinated aromatic components.
• Material Science: Serves as a monomer or building block for creating advanced organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Ligand Synthesis: Employed in the development of novel catalysts and ligands for asymmetric synthesis and other transition metal-catalyzed processes.
• Chemical Biology & Proteomics: Useful in the design and synthesis of molecular probes and inhibitors that target specific enzymes or biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CROs/CMOs serving the life sciences sector.

Basic Information

Product Name	3,5-Difluoro-4-Propoxyphenylboronic Acid
CAS No.	2096331-43-8
Molecular Formula	C9H11BF2O3
Molecular Weight	216.00 g/mol
Synonyms	4-Propoxy-3,5-difluorophenylboronic Acid; (3,5-Difluoro-4-propoxyphenyl)boronic Acid; B-(3,5-Difluoro-4-propoxyphenyl)boronic Acid; 3,5-Difluoro-4-propoxybenzeneboronic Acid; 2096331-43-8; 4-(Propoxy)-3,5-difluorobenzeneboronic Acid
EINECS	Contact for details

Quality Control

Every batch of 3,5-Difluoro-4-Propoxyphenylboronic Acid is produced under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.