Description

5-(Benzyloxy)-2-Fluoro-3-(Trifluoromethyl)Phenylboronic Acid is a high-purity, advanced boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the precise construction of complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique fluorinated and benzyl-protected structure offers valuable synthetic versatility.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing complex, fluorinated biaryl compounds targeted in drug discovery programs.
• Agrochemical Research: Used in the development of new herbicides and pesticides, where the introduction of fluorine atoms can enhance biological activity and environmental stability.
• Material Science: Employed in the synthesis of organic electronic materials, such as ligands for OLEDs or charge-transport molecules, leveraging its boronic acid functionality.
• Chemical Biology: Acts as a versatile handle for bioconjugation and the synthesis of molecular probes and sensors due to its selective reactivity.
• Academic & Process R&D: Serves as a valuable reagent for methodological development in organic synthesis and scaling up novel reaction pathways.

Basic Information

Product Name	5-(Benzyloxy)-2-Fluoro-3-(Trifluoromethyl)Phenylboronic Acid
CAS No.	2096331-25-6
Molecular Formula	C14H11BF4O3
Molecular Weight	314.05 g/mol
Synonyms	[2-Fluoro-5-(phenylmethoxy)-3-(trifluoromethyl)phenyl]boronic acid; 5-(Benzyloxy)-2-fluoro-3-trifluoromethylbenzeneboronic acid; 2-Fluoro-5-(benzyloxy)-3-(trifluoromethyl)phenylboronic acid; Boronic acid, B-[2-fluoro-5-(phenylmethoxy)-3-(trifluoromethyl)phenyl]-; 2096331-25-6; 5-Benzyloxy-2-fluoro-3-trifluoromethylphenylboronic acid
EINECS	Contact for details

Quality Control

Every batch of 5-(Benzyloxy)-2-Fluoro-3-(Trifluoromethyl)Phenylboronic Acid is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, NMR, and elemental analysis, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric oxygen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.