Description

3-Chloro-4-Fluoro-5-Propoxyphenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in enabling precise Suzuki-Miyaura cross-coupling reactions, a cornerstone method for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting CNS disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science: Serves as a monomer or cross-linking agent in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Ligand & Catalyst Development: Employed in the preparation of sophisticated ligands for transition metal catalysis and organocatalysis.
• Chemical Biology & Proteomics: Utilized in the synthesis of molecular probes and affinity tags for studying protein function and interactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs serving the global life sciences market.

Basic Information

Product Name	3-Chloro-4-Fluoro-5-Propoxyphenylboronic Acid
CAS No.	2096331-01-8
Molecular Formula	C9H11BClFO3
Molecular Weight	231.45 g/mol
Synonyms	(3-Chloro-4-fluoro-5-propoxyphenyl)boronic Acid; 3-Chloro-4-fluoro-5-propoxybenzeneboronic Acid; 5-Propoxy-3-chloro-4-fluorophenylboronic Acid; Boronic acid, B-(3-chloro-4-fluoro-5-propoxyphenyl)-; CAS 2096331-01-8
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-4-Fluoro-5-Propoxyphenylboronic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.