Description

4-Butoxy-3,5-Difluorophenylboronic Acid is a specialized organoboron compound featuring a butoxy-substituted difluorophenyl ring. This boronic acid derivative is a critical building block in modern synthetic chemistry, particularly valued for its role in Suzuki-Miyaura cross-coupling reactions. It is primarily utilized by pharmaceutical R&D and advanced material science laboratories for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing difluorophenyl motifs.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boron reagent for forming carbon-carbon bonds to create biaryl structures in drug discovery and material science.
• Agrochemical Research: Used in the development of novel herbicides and pesticides where the difluorophenyl group imparts specific biological activity.
• Liquid Crystal & OLED Material Synthesis: Employed in the construction of organic electronic materials and advanced display components.
• Polymer Chemistry: Acts as a monomer or functionalization agent for creating specialty polymers with tailored properties.
• Chemical Biology & Probe Development: Useful for synthesizing molecular probes and ligands for biochemical assays and diagnostic applications.

Basic Information

Product Name	4-Butoxy-3,5-Difluorophenylboronic Acid
CAS No.	2096329-78-9
Molecular Formula	C₁₀H₁₃BF₂O₃
Molecular Weight	230.02 g/mol
Synonyms	(4-Butoxy-3,5-difluorophenyl)boronic acid; 3,5-Difluoro-4-butoxyphenylboronic acid; 4-Butoxy-3,5-difluorobenzeneboronic acid; Boronic acid, B-(4-butoxy-3,5-difluorophenyl)-; 2096329-78-9; 4-n-Butoxy-3,5-difluorophenylboronic Acid
EINECS	Contact for details

Quality Control

Our 4-Butoxy-3,5-Difluorophenylboronic Acid is manufactured under strict quality protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.