Description

3-Methoxy-4-(trifluoromethoxy)phenylboronic acid is a specialized organoboron compound widely utilized as a key building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing complex aromatic and heteroaromatic systems.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific trifluoromethoxy-substituted aromatic motifs.
• Material Science: Serves as a building block for creating novel organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and semiconductors.
• Ligand & Catalyst Development: Employed in the preparation of sophisticated ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new chemical spaces and synthesizing libraries of compounds for screening.
• Liquid Crystal & Polymer Chemistry: Used as a monomer or intermediate in the synthesis of specialty polymers and liquid crystal materials with tailored properties.

Basic Information

Product Name	3-Methoxy-4-(trifluoromethoxy)phenylboronic Acid
CAS No.	2096329-73-4
Molecular Formula	C8H8BF3O4
Molecular Weight	235.96 g/mol
Synonyms	[3-Methoxy-4-(trifluoromethoxy)phenyl]boronic acid; (3-Methoxy-4-(trifluoromethoxy)phenyl)boronic acid; Boronic acid, B-[3-methoxy-4-(trifluoromethoxy)phenyl]-; 3-Methoxy-4-trifluoromethoxybenzeneboronic acid; 4-Trifluoromethoxy-3-methoxyphenylboronic acid; 3-Methoxy-4-(trifluoromethoxy)benzeneboronic acid
EINECS	Contact for details

Quality Control

Our 3-Methoxy-4-(trifluoromethoxy)phenylboronic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance in regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from incompatible materials such as strong oxidizers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.