Description

3-Butoxy-2,4-Difluorophenylboronic Acid is a specialized organoboron compound featuring a butoxy substituent and fluorine atoms on the phenyl ring, making it a valuable building block in modern synthetic chemistry. Its primary value lies in its role as a key intermediate in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. This high-purity boronic acid is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where precise molecular assembly is critical for developing new active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A crucial precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting complex biaryl structures.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the difluorophenyl moiety can enhance biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs or organic semiconductors.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and tags for studying biological processes and diagnostics.
• Catalyst & Ligand Preparation: Acts as a starting material for synthesizing specialized ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: A key raw material for fine chemical and CDMO companies producing bespoke compounds for client R&D and scale-up projects.

Basic Information

Product Name	3-Butoxy-2,4-Difluorophenylboronic Acid
CAS No.	2096329-70-1
Molecular Formula	C₁₀H₁₃BF₂O₃
Molecular Weight	230.02 g/mol
Synonyms	(3-Butoxy-2,4-difluorophenyl)boronic acid; 2,4-Difluoro-3-butoxybenzeneboronic acid; B-(3-Butoxy-2,4-difluorophenyl)boronic acid; 3-Butoxy-2,4-difluorobenzeneboronic acid; (2,4-Difluoro-3-butoxyphenyl)boronic acid; Boronic acid, B-(3-butoxy-2,4-difluorophenyl)-; 2096329-70-1
EINECS	Contact for details

Quality Control

Our 3-Butoxy-2,4-Difluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the high standards required for sensitive cross-coupling applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.