Description

2-Fluoro-3-Methoxy-5-Methylphenylboronic Acid is a specialized organoboron compound that serves as a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing complex fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific fluorinated aromatic motifs for enhanced activity.
• Material Science Research: Building block for creating novel organic electronic materials, liquid crystals, and polymers where precise fluorine substitution is required.
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and labeled compounds for biochemical and diagnostic applications.
• Catalyst & Ligand Development: Serves as a starting material for synthesizing specialized ligands and catalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A critical reagent for fine chemical and custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	2-Fluoro-3-Methoxy-5-Methylphenylboronic Acid
CAS No.	2096329-52-9
Molecular Formula	C8H10BFO3
Molecular Weight	183.98 g/mol
Synonyms	(2-Fluoro-3-methoxy-5-methylphenyl)boronic acid; 2-Fluoro-3-methoxy-5-methylbenzeneboronic acid; 5-Methyl-2-fluoro-3-methoxybenzeneboronic acid; Boronic acid, B-(2-fluoro-3-methoxy-5-methylphenyl)-; 2096329-52-9; 2-Fluoro-3-methoxy-5-methyl-phenylboronic acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-Methoxy-5-Methylphenylboronic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP guidelines where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation and maintain purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.