Description

Phosphine Oxide, Dimethyl[3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]- is a high-value organoboron compound featuring a phosphine oxide functional group. This unique structure makes it a critical ligand precursor and versatile building block in advanced synthetic chemistry. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and materials science sectors for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a key boronic ester reagent for forming carbon-carbon bonds in complex molecule synthesis.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Ligand Synthesis for Catalysis: Acts as a precursor for phosphine-based ligands used in homogeneous catalysis, including palladium-catalyzed transformations.
• Agrochemical Development: Employed in creating novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Organic Light-Emitting Diode (OLED) Materials: Utilized as a building block for electron-transport or host materials in display and lighting technologies.
• Polymer and Resin Modification: Incorporated into specialty polymers to impart specific thermal, optical, or mechanical properties.
• Academic and Industrial Research: A valuable tool for methodological development and exploring new chemical spaces in medicinal and synthetic chemistry.

Basic Information

Product Name	Phosphine Oxide, Dimethyl[3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-
CAS No.	2093110-21-3
Molecular Formula	C16H26BFO3P
Molecular Weight	334.16 g/mol
Synonyms	(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)dimethylphosphine oxide; Dimethyl(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)phosphine oxide; 3-(Dimethylphosphinyl)phenylboronic acid pinacol ester; 3-(Dimethylphosphoryl)phenylboronic acid pinacol ester; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N,N-dimethylbenzenephosphonamidic acid oxide; B-[3-(Dimethylphosphinyl)phenyl]boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our production of Phosphine Oxide, Dimethyl[3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]- adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your critical syntheses. Each lot is analyzed using advanced techniques including NMR, HPLC, and GC to verify identity, purity, and impurity profiles. Comprehensive Certificates of Analysis (COA) documenting all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.