Description

2-{3-Fluorobicyclo[1.1.1]Pentan-1-Yl}Acetic Acid is a high-value, structurally complex fluorinated building block essential for advanced organic synthesis. This compound is critical for medicinal chemistry research, enabling the rapid exploration of novel chemical space and the development of new therapeutic candidates. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers focused on creating next-generation small molecule drugs and agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon for incorporating the rigid, three-dimensional bicyclo[1.1.1]pentane scaffold with a fluorine handle into drug candidates, potentially improving metabolic stability and binding affinity.
• Medicinal Chemistry Research: Used in fragment-based drug discovery and lead optimization programs to explore structure-activity relationships (SAR) and modulate physicochemical properties.
• Agrochemical Synthesis: Serves as a building block for developing novel, potent active ingredients with potentially enhanced environmental profiles.
• Material Science Precursor: Can be utilized in the synthesis of specialty polymers or advanced materials where the unique steric and electronic properties of the fluorinated bicyclic system are beneficial.
• Chemical Biology Probe Development: Employed to create tool compounds for studying biological targets and pathways due to its ability to serve as a bioisostere for common aromatic rings.

Basic Information

Product Name	2-{3-Fluorobicyclo[1.1.1]Pentan-1-Yl}Acetic Acid
CAS No.	2092067-90-6
Molecular Formula	C7H9FO2
Molecular Weight	144.14 g/mol
Synonyms	2-(3-Fluorobicyclo[1.1.1]pentan-1-yl)acetic acid; 3-Fluoro-1-bicyclo[1.1.1]pentanylacetic Acid; 2-(3-Fluorobicyclo[1.1.1]pentan-1-yl)ethanoic acid; 1-(Carboxymethyl)-3-fluorobicyclo[1.1.1]pentane; 3-Fluorobicyclo[1.1.1]pentane-1-acetic acid; BCP-F-AcOH; Fluorinated Bicyclopentyl Acetic Acid
EINECS	Contact for details

Quality Control

Our production of 2-{3-Fluorobicyclo[1.1.1]Pentan-1-Yl}Acetic Acid adheres to stringent quality management protocols. Every batch is characterized and tested using advanced analytical techniques, including NMR, HPLC, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for each lot, supporting cGMP-compliant development workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its acidic nature, keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.