Description

5-Amino-4-Bromo-2-Methoxy-Benzonitrile is a high-purity, multi-functional aromatic nitrile building block. This compound is valued for its unique substitution pattern, which makes it a versatile intermediate in advanced organic synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for constructing complex molecular architectures, such as active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its bromo and amino groups for further functionalization.
• Material Science Research: Serves as a building block for organic electronic materials, including organic light-emitting diodes (OLEDs) and semiconductors.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing specialized azo dyes and high-performance pigments.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig aminations.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for biochemical research and diagnostic applications.

Basic Information

Product Name	5-Amino-4-Bromo-2-Methoxy-Benzonitrile
CAS No.	2091537-83-4
Molecular Formula	C8H7BrN2O
Molecular Weight	227.06 g/mol
Synonyms	4-Bromo-5-amino-2-methoxybenzonitrile; 2-Methoxy-4-bromo-5-aminobenzonitrile; Benzonitrile, 5-amino-4-bromo-2-methoxy-; 5-Amino-4-bromo-2-methoxybenzonitrile; 4-Bromo-2-methoxy-5-aminobenzonitrile; 2-Methoxy-5-amino-4-bromobenzonitrile
EINECS	Contact for details

Quality Control

Our 5-Amino-4-Bromo-2-Methoxy-Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC Area %)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.