Description

5-Amino-4-Chloro-2-Methoxy-Benzonitrile is a high-purity, multi-functional aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring amino, chloro, and methoxy substituents, makes it a versatile intermediate for constructing complex heterocyclic systems and fine chemicals. This compound is primarily sought by research and development laboratories and production facilities in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for constructing fused heterocycles and complex molecular scaffolds.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its reactive sites for structural diversification.
• Dye and Pigment Manufacturing: Serves as a building block for creating specialized azo dyes and high-performance pigments due to its aniline derivative core.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and other functional organic materials.
• Cross-Coupling Reactions: The chloro and amino groups make it a suitable substrate for palladium-catalyzed reactions like Buchwald-Hartwig amination or Suzuki couplings.
• Academic & Contract Research: A valuable reagent for methodological studies and custom synthesis projects in university and CRO laboratories.

Basic Information

Item	Detail
Product Name	5-Amino-4-Chloro-2-Methoxy-Benzonitrile
CAS No.	2090998-18-6
Molecular Formula	C8H7ClN2O
Molecular Weight	182.61 g/mol
Synonyms	4-Chloro-5-amino-2-methoxybenzonitrile; 2-Methoxy-4-chloro-5-aminobenzonitrile; 5-Amino-4-chloro-2-methoxybenzonitrile; Benzonitrile, 5-amino-4-chloro-2-methoxy-; 4-Chloro-2-methoxy-5-aminobenzonitrile; 2-Methoxy-5-amino-4-chlorobenzonitrile
EINECS	Contact for details

Quality Control

Every batch of 5-Amino-4-Chloro-2-Methoxy-Benzonitrile is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment. Our quality protocols are designed to support cGMP and ISO compliant workflows for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.